- 期刊
Radiation Therapy for Trichoepithelioma: Case Report
毛髮上皮瘤的放射線治療：病例報告
摘要
目的：毛髮上皮瘤是一種罕見的源於毛囊的皮膚腫瘤，好發於頭頸部如頭皮、額頭、鼻子、臉部和唇部，常引起美觀上的困擾或是功能上的障礙，我們報告一例多發性毛髮上皮瘤放射線治療之顯著治療成果。 病例報告：一名57歲的婦女發現罹患許多毛髮上皮瘤於兩側的眉毛上，三年多來她接受過許多種治療，包括塗抹類固醇及其他不明的藥物；口服抗生素、冷凍治療、磨皮手術及雷射治療等等均無效，後來她接受50Gy 20次的6百萬電子伏特的電子射線放射治療，腫瘤因此得到完全緩解，治療至今已18個月，沒有腫瘤復發的跡象且外觀正常，沒有美觀上的困擾。 結論：對於經過治療失敗或是因治療會引起美觀或是功能障礙的毛髮上皮瘤而言，放射線治療的效果也很好，應是另一個選擇。
並列摘要
Background: Trichoepithelioma is a rare skin tumor that arises from hair follicles. The most common locations are in the scalp, forehead, nose and upper lip and can cause significant cosmetic and functional impairment. In this study, we report a case of multiple trichoepitheliomas treated by radiation therapy which demonstrated a dramatic response with a significant cosmetic improvement. Case: A 57-year-old woman suffered from multiple coalesced lesions of trichoepitheliomas in her bilateral eyebrows for three years. She had received numerous treatments including topical steroid and unknown drugs use, oral antibiotics, cryotherapy, dermabrasion and laser surgery which all had failed. She then received radiation therapy with 50Gy in 20 fractions by 6-MeV electron beams. She is free of tumor in the irradiated area 18 months after treatment with significant cosmetic improvement. Conclusion: Radiation therapy should be an alternative for patients with trichoepitheliomas who have failed other forms of treatment and those with multiple coalesced lesions that cause significant cosmetic or functional impairment.