- 期刊
Synovial Sarcoma of Upper Extremity-A Lethal Disease-Two Cases Report
上肢之滑液膜惡性肉瘤－一種致命性之疾病－兩病例報告
摘要
滑液膜惡性肉瘤大多發生於肢體，好發在較大之關節附近，尤其在膝部。而牽連至上肢的滑液膜惡性肉瘤則相對地十分罕見。從2000年3月至2003年2月，本院整形外科共治療二例上肢之滑液膜惡性肉瘤的患者，分別發生於腕部及肘部。兩名病例先前均由骨科醫師執行切片手術。隨後會診本院整形外科做進一步之廣泛性切除與重建手術。兩名病例分別於接受第一次切片手術後24及29個月因肺部轉移而死亡。上肢之滑液膜惡性肉瘤是一種十分具有侵略性與致命性的惡性腫瘤，立即根除性的手術，甚至截肢，配合術後放射或化學治療，對病患之預後是有利的。在文中我們將詳盡地討論它的診斷、治療、病理檢查以及預後。
關鍵字
無資料並列摘要
Synovial sarcomas occur predominantly in the extremities, where they tend to arise in the general vicinity of large joints, especially the knee. Upper-extremity involvement is relatively rare. From March 2000 to February 2003, two cases of synovial sarcoma of the upper extremity were treated, one proximate to the wrist and the other close to the elbow. Both cases underwent excisional biopsy by orthopedic surgeons. We were subsequently consulted for further wider excision and reconstruction for the resultant defect. Both cases subsequently died due to lung metastases 24 months and 29 months subsequent to their excisional biopsies. Because a synovial sarcoma is a very aggressive and lethal malignancy, prompt and radical surgery even amputation is recommended, and subsequent radiotherapy or chemotherapy may be used in conjunction with surgery. Finally, we will discuss the diagnosis, treatment, and pathology of and prognosis for this tumor.