Ofuji氏丘疹紅皮症是一不常見的發炎性皮膚病,臨床表現相當具有特徵,包括由許多發癢性紅色丘疹融合成之紅皮症樣全身性皮疹、身體主要皮膚縐摺處未受侵犯〈deck-chair徵象〉、及許多病人血中嗜依紅性白血球升高等變化。而特別值得注意的是有些病人會合併有內部器官的惡性腫瘤。在此報告二位老年的男性病患,他們均出現典型Ofuji氏丘疹紅皮症的皮膚變化,經口服抗組織胺和外用類固醇的治療,其中一病患另併用紫外線B光照射療法,患者的皮疹皆得到短期的緩解。兩位患者接受一系列的檢查均未發現合並併內臟器官腫瘤。
Papuloerythroderma of Ofuji (PEO) is a rare inflammatory dermatosis with characteristic clinical features including numerous itching confluent papules, sparing of major body folds (the deck-chair sign), and peripheral blood eosinophilia in many patients. It may sometimes be associated with an internal malignancy. We report two old male patients with typical skin rashes of PEO which were transiently controlled with oral antihistamines and topical corticosteroids with and without combining UVB phototherapy, respectively. A series of investigations failed to show any evidence of internal malignancy in either patient.