- 期刊
Acantholytic Acanthoma -Two Case Reports-
棘層鬆解性棘皮瘤─二例病例報告─
摘要
棘層鬆解性棘皮首先於1985年由Brownstein提出，是一種先前尚未被分類的良性棘皮瘤。本篇文章報告二例具有典型病理變化之棘層鬆解性棘皮瘤。第一例是一位62歲男性病人，在其左側腋下發現一個米粒大小，紅色具有彈性，硬的圓形小丘疹。組織病理學檢查發現表皮層有局部棘皮層增生，以及基底層裂隙和棘層鬆解的現象。第二例為一位68歲女性病人，在其右上臂發現一個咖啡色，蠶豆大小的斑塊，其組織病理學檢查可以發現在表皮層有顆粒層及棘皮層的增生，並伴隨有明顯的基底層裂隙和棘層鬆解的現象。本文並討論了其他需要與棘層鬆解性棘皮瘤鑑別診斷的疾病。
關鍵字
無資料並列摘要
Acantholytic acanthoma is a benign acanthoma unrecognized previously, which was first described by Brownstein in 1985. Here we report two cases of acantholytic acanthoma, the first case was a 62-year-old male patient presented with one erythematous, hyperkeratotic, rice grain-sized papule with elastic, firm consistency over his left axilla for several months. Histopathological examination of excisional biopsy revealed focal acanthosis with suprabasal clefts and intraspinous acantholysis of epidermis. The second case was a 68-year-old female patient presented with one brownish, bean-sized, hyperkeratotic plaque on her right upper arm for several months without any symptom. Microscopic study showed hypergranulosis and acanthosis with prominent suprabasal clefts and intraspinous acantholysis of epidermis. Both of these two cases were typical acantholytic acanthoma with characteristic histopathologic features and differentiations from other disease with acantholytic dyskeratosis were also mado.