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Protein Contact Dermatitis-A Case Report

蛋白質接觸性皮膚炎-病例報告

摘要


蛋白質接觸性皮膚炎是一種獨特的職業性皮膚炎。臨床上,病患手部接觸到過敏的食物後不久,即出現激癢的水泡。這是一個透過合併第一型及第四型過敏,或是單獨由第一型過敏機轉所導致的反應。診斷依賴皮膚針刺或搔破試驗。我們報告的病例,是位久為手部慢性溼疹所苦的28歲男性麵包師傅。近6年來,每每在處理某些特定食物後,手上就會出現發癢的小水泡。經過皮膚針刺試驗,診斷此病患對小黃瓜、蛋白及蛋黃有蛋白質接觸性皮膚炎。我們報告此病例,並對相關文獻加以回顧及整理。

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並列摘要


Protein contact dermatitis is a unique occupational dermatitis with a characteristic episodic, eczematous, itchy vesicular eruption mostly on the hands of food handlers. It usually develops several minutes after handling the offending allergens. It is either a combined type Ⅰ and type Ⅳ or a type Ⅰ hypersensitivity reaction alone. The diagnosis is made by skin prick or scratch test using the causative agents. We report such a case in a 28-year-old baker, a patient with chronic hand eczema, who had a 6-year history of a pruritic vesicular rash immediately after handling certain foods. A diagnosis of protein contact dermatitis was made by demonstrating positive reaction to a prick test with cucumber, egg white, and egg yolk.

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