散播型表淺性日光性汗孔角化症之過度角化變異型－癢疹之擬仿者

The Hyperkeratotic Variant of Disseminated Superficial Actinic Porokeratosis-A Prurigo Simulator

蔡佳茂(Chia-Mao Tsai) ； 蔡呈芳(Tsen-Fang Tsai) ； 郭峰昇(Feng-Sheng Kuo) ； 陳佑甫(Yu-Fu Chen) ； 洪志明(Chih-Ming Hung)

《中華皮膚科醫學雜誌》 25卷1期 (2007/03) Pp. 59-66

https://doi.org/10.29784/DS.200703.0011

摘要

散播型表淺性日光性汗孔角化症(DSAP)是一種遺傳性疾病，主要侵犯四肢，尤其容易在日光曝曬區域出現。病灶之典型表現為周圍隆起、中央略為萎縮的丘疹或斑塊。病理檢驗在表皮內呈現柱狀角化不全，特曰：「雞眼樣薄板層」(cornoid lamella)為其特徵。DSAP並非罕見疾病，但過度角化之變異型則甚少見。僅有一例被報導。在此吾人報告一位81歲男性，呈現DSAP之過度角化變異型症之臨床與病理變化，此類型DSAP常與其他良性或早期惡性角化症混淆，臨床上需要特別留意。

並列摘要

Disseminated superficial actinic porokeratosis (DSAP) is a hereditary disease which involves mainly the extremities, especially sun-exposed areas. The typical lesions show papules or plaques with slightly atrophic centers and peripheral ridges, and the pathological features reveal characteristic cornoid lamella-a parakeratotic column on the epidermis. DSAP is not a rare disease, but the hyperkeratotic variant is uncommon. Only one case was reported previously. We report a 81-year-old man whose clinical and pathological finding was consistent with hyperkeratotic variant of DSAP. This form of DSAP is often misdiagnosed as other benign or premalignant keratosis and warrants special clinical consideration.

並列關鍵字

Hyperkeratotic ； Disseminated superficial actinic porokeratosis