「前額纖維化禿髮」的臨床特徵是發生於前額至兩側顳部之進行性帶狀疤痕性禿髮,常伴隨眉毛掉髮。在掉髮活性高的邊緣地帶常可以見到具特色之毛孔角化。此病症之組織學變化則與毛孔扁平苔癬類似。直至今日,全世界已有超過80個案例被報告,其中大部分的前額纖維化禿髮發生於停經之女性,但亦可發生於停經前之女性,甚至是男性都曾被報告過。在此,我們報告一例發生於停經前女性之前額纖維化禿髮並討論此疾病的鑑別診斷、組織病理學變化及其治療。前額纖維化禿髮是一種以往較少被辨認出的禿髮疾病,隨著越來越多相關的報告來描繪此疾病,應該可以避免將前額纖維化禿髮與其它禿髮的診斷混淆。
Clinically, frontal fibrosing alopecia (FFA) is characterized by hand-like scarring alopecia anterior to the recessed frontotemporal hairline in a progressive course and often accompanied by eyebrow loss, The unique feature of follicular keratosis is often observed at the active margin. Histologically, it resembles lichen planopilaris (LPP). To dale, more than 80 eases of FFA has e been described in the literature. The majority of FFA was observed in postmenopausal women although this disease has also been found in males and premenopausal females. Hererin, we describe a case of FFA in a premenopausal woman and discuss the differential diagnosis. histopathogenesis, and treatment. FFA is probably an under-recognized alopecia. With increasing reports to delineate this disease, the confusion with other types of alopecia can be as sided.