- 期刊
Ofuji's Disease: A Review of 34 Patients in 10 Years
太藤氏病：十年內三十四位病人之回顧
摘要
太藤氏病，臨床上為慢性、反覆發作之環狀板塊，伴有毛孔一致性之丘疹及膿疱散佈其上，且有中央消散及向外擴張的情形。此病之致病機轉目前尚不明，但indomethacin被認為是首選治療藥物。雖然文獻上所報告的太藤氏病病例大多為日本人，依我們的經驗，此病在台灣也並不罕見。在此回溯過去十年間，來本科求診，經切片確診之34例太藤氏病患者。我們發現，34例病患中有高達15例(44%)出現臉部以外之病灶，其中有7例出現手掌腳掌病灶。由於極易造成臨床上與病理上之混淆而延誤診斷，我們在此特別強調此臉部外病灶之臨床表現。我們也發現在本研究的病例中，使用indomethacin治療似有較佳之療效，其治療之有效率為89%。
關鍵字
無資料並列摘要
Ofuji's disease is clinically characterized by chronic and recurrent annular clusters of sterile follicular papules and pustules superimposed on plaques with central clearing and peripheral extension. Indomethacin is considered to be a first choice of treatment, but the pathogenesis of this disease is still obscure. Although most cases of Ofuji's disease have been reported in Japanese people, it is not rare in Taiwan according to our clinical experience. In this study, we reviewed 34 patients with biopsy-proven Ofuji's disease who came to our clinic over the past decade. Extrafacial involvement was noted in 15 of 34 patients (44%), and 7 had palmoplantar lesions. We emphasize on the features of extra-facial involvement, especially the palmoplantar lesions, because it may lead to clinical and pathological confusion in diagnosing the disease. We also found indomethacin seemed to have a higher effective rate (89%) as compared to other treatments in our cases.