生物活性玻璃的效果：文獻回顧

Effect of Bioactive Glass: Literature Review

顏瑞瑩(Jui-Ying Yen) ； 林怡君(Yi-Chun Lin) ； 陳恆理(Hen-Li Chen) ； 賴玉玲(Yu-Lin Lai)

《臺灣牙周病醫學會雜誌》 13卷2期 (2008/06) Pp. 139-146

https://doi.org/10.6121/TAP.200806_13(2).0004

摘要

生物活性玻璃爲一具有生物相容性的人工合成移植骨，廣泛應用於骨科及牙科。臨床上，生物活性玻璃可單獨使用或合併使用其他骨移植物進行牙周手術的骨缺損填補、骨豐隆術、骨（山 脊）保留術或充當上顎提升的移植骨。本文藉文獻回顧介紹生物活性玻璃的主要成份、探討生物活性玻璃於骨缺損中骨組織的癒合情形並比較生物活性玻璃與其他骨移植物或再生材料於不同適應症的臨床效果。近來的研究指出生物活性玻璃與目前所使用的生物材料的臨床效果相似，並且發現使用生物活性玻璃可改善患者的骨缺損。

關鍵字

生物活性玻璃 ； 骨缺損 ； 治療效果

並列摘要

Bioactive glass is one of biocompatible alloplasts and widely applied in the field of orthopedics and dentistry. Clinically, bioactive glass can be single use or in combination with other graft materials as a bone substitute for periodontal defects, bone augmentation, ridge preservation or sinus grafting procedure. This article will introduce the main composition of bioactive glass particles and discuss the bone healing around this alloplast in the bony defect. A comparison of clinical effects of bioactive glass with other osseous graft materials or some regenerative materials in various clinical indications is presented in detail. The recent investigations demonstrate that the clinical effect of bioactive glass is similar to those of the various biomaterials currently available and the application of bioactive glass can result in improved treatment outcomes for the patients with osseous defects.

並列關鍵字

bioactive glass ； osseous defect ； treatment outcome