- 期刊
慢性腎臟病與牙周病之關聯性
Association between Chronic Kidney Disease and Periodontitis
摘要
慢性腎臟病的定義是腎臟結構或功能上的異常，並依腎絲球過濾率從輕微到嚴重分為五期，越低代表腎功能越差，心血管疾病的風險和死亡率也隨之增加。台灣的慢性腎臟病盛行率在世界各國中名列前茅，影響國人的健康也耗費龐大的醫療資源。牙周病是發炎性疾病，會造成牙齒支持組織的破壞，包括牙周韌帶和齒槽骨，牙周病和慢性腎臟病有許多相同的風險因子，例如抽煙、年齡以及控制不佳的糖尿病，也越來越多證據支持牙周病和慢性腎臟病的關聯性。本篇文章的目的旨在探討慢性腎臟病患者的牙周狀況、牙周病和慢性腎臟病之關聯性以及非手術性牙周治療是否可以改善患者的腎臟功能。回顧文獻發現慢性腎臟病患者相較於健康成人，前者牙周病的進展較顯著，血液透析患者尤為明顯；大部分文獻認為牙周病可能會增加CKD發生的風險，而目前對於牙周治療是否可以改善腎功能則尚無定論。
並列摘要
Chronic kidney disease(CKD) is defined as an abnormality in the structure or function of the kidney, and is divided into five stages according to the glomerular filtration rate from mild to severe. As the disease progresses, patients' renal function decreases, and the comorbidities such as cardiovascular disease and mortality increases. The prevalence of chronic kidney disease in Taiwan ranks among the highest in the world, affecting people's health and presenting huge medical burden. Periodontal disease is an inflammatory disease that causes the destruction of tooth-supporting tissues, including the periodontal ligament and alveolar bone. Periodontal disease and chronic kidney disease share many of the same risk factors, such as smoking, age, and poorly controlled diabetes. There is also increasing evidence supporting the association between periodontal disease and chronic kidney disease. The objective of this article is to evaluate the periodontal status of patients with chronic kidney disease, the association between periodontal disease and chronic kidney disease, and whether non-surgical periodontal treatment can improve patient's renal function . Literature review found that compared with healthy adults, the progression of periodontitis was more significant in patients with chronic kidney disease, especially in hemodialysis patients; most of the studies showed that periodontitis may increase the risk of CKD, but the current research on whether periodontal treatment can improve renal function is still inconclusive.