Gingival recession will cause not only esthetic problems but also possible root sensitivity. Thus, affecting the patient's life quality. Clinically, there are many different root coverage surgical methods treating gingival recession. Among these methods, coronally advanced flap(CAF)combined connective tissue graft(CTG)can lead to the best long-term stability of the root coverage. Also, an increase in the width of keratinized gingiva. As for enamel matrix derivative(EMD), it can promote wound healing and periodontal regeneration. Thus, coronally advanced flap combined with usages of enamel matrix derivative is also commonly discussed as an alternative by several authors. This case series will provide two case reports using different surgical methods as discussed above(CAF+CTG; CAF+EMD)to perform bilateral root coverage surgery. Results: The patient from Case 1 received root coverage surgery using CAF+EMD. The gingival recession of tooth 13.23 improved from 2.5mm to 1mm after root coverage. The patient from Case 2 received root coverage surgery using CAF+CTG. The gingival recession of tooth 13.23 was 3 mm and 3.5 mm, respectively, and post-op results were both 0 mm, achieving full coverage of the roots. Conclusion: From this case series, the amount of root coverage is predictable by either of these two methods (CAF+EMD or CAF+CTF).