Although the prevalence of aggressive periodontitis (AgP) is only about 1% among the Asian population, it is usually difficult to make treatment decisions about this disease due to its rapid progression and the complexity of its etiological factors, both of which make the outcome quite unpredictable. The aim of this article is to provide evidence-based guidelines for the treatment of aggressive periodontitis. We summarize the disease's diagnostic criteria, its etiological factors, its prevalence, and its progression pattern. Based on a systematic electronic literature search, a recent systematic review, and the classic literature on the subject, the therapeutic efficiency of the various treatment strategies available for AgP patients are discussed, including treatment protocols such as systemic antibiotics, the feasibility of implant therapy and protocols used for supportive care after treatment. According to current clinical evidence and the disease's physiological characteristics, the progression and severity of AgP in the Taiwanese population may be higher than that in Western populations. Adjunctive antibiotic treatment together with intense follow up is recommended when treating AgP patients in Taiwan.
侵襲性牙周炎在亞洲族群約發生率接近1%,雖相較於慢性牙周炎少見許多,但因其破壞速度相對較快、致病因子也相對複雜,造成治療上的困難性以及不可預期性。本篇文獻回顧的目標是針對「侵襲性牙周炎」這個主題做出有實證醫學基礎的治療建議及指引。本文自診斷、致病因子等面向切入,分析疾病發生率及進程,並透過系統性統整牙周病治療現有臨床研究、系統性回顧及經典文獻,瞭解非手術與手術療程對侵襲性牙周炎療效,及適用之抗生素療程,亦對於積極性牙周治療完成後的植牙及支持性牙周治療進行討論。基於現有臨床證據及生理特徵差異,臺灣族群侵襲性牙周炎侵犯速度與嚴重度可能更為劇烈,建議可於療程中結合抗生素治療,並予以較頻繁的回診維護。