- 期刊
使用聚對二氧環己酮縫合線在引導骨再生手術：病例系列
Application of Polydioxanone Suture in Guided Bone Regeneration: Case Series
摘要
研究目的：在重建水平骨缺損中，使用可吸收再生膜與骨粉已經是廣泛運用的方式，特別是在凹陷或是有殘留骨壁的骨缺損。然而，由於可吸收再生膜柔軟的特性，在平坦或是沒有殘留骨壁的骨缺損，可能需要額外穩定再生材料的。可吸收的聚對二氧環己酮縫合線（PDS II, polydioxanone suture），這種衍生聚酯材料已被應用於醫療材料中超過40年。它可以同時有足夠的機械強度和緩慢的降解速率，會在體內逐漸吸收。可以在可吸收膜與骨粉下提供支撐的空間，提供成骨穩定的環境。本篇病例系列報告目標是討論PDS II與骨再生的應用，並對臨床治療結果提出探討和評估。材料與方法：本篇報告包括兩名病例，皆因植牙需要進行骨再生（bone regeneration），一名在植牙的同時進行骨再生手術，另一名先進行骨再生後8個月再進行植牙手術。結果：兩個病例的植體周圍無論是在x光影像還是在臨床上皆有良好的硬質地骨再生。追蹤植體使用半年至一年，植體周圍骨水平皆穩定。結論：PDS II線可以提供許多優勢，包括足夠的機械強度、可吸收性、較無侵入性的手術與費用。未來可以提供更多的案例與對照組，進一步討論其優缺點。
並列摘要
The application of resorbable membranes and bone grafts in regeneration of horizontal bone deficiency, especially in contained defects, has been widely used. However, in some flat and non-contained bony defects, the further stabilization of resorbable membrane may be needed because of the softness of resorbable regenerative membranes. The resorbable polydioxanone suture (PDS II), a derivative polyester material, has been applied in medical field for over 40 years. It possesses both sufficient mechanical strength and a slow degradation rate, gradually being absorbed in the body. It can provide support of resorbable membranes and bone grafts, creating a stable environment for bone formation. The goal of this report is to discuss the application of PDS II in bone regeneration and evaluation of clinical treatment outcomes. Materials and Methods: This report includes two cases, both requiring bone augmentation for dental implant placement. In one case, guided bone regeneration was performed simultaneously with the implant placement, while in the other case, bone augmentation was performed first, followed by implant surgery after an 8-month interval. Results: In both cases, excellent hard tissue regeneration was observed around the implants, in both radiographic images and clinical assessments. Over the period of six months to one year post implant loading follow up, the bone levels around the implants remained stable, indicating successful integration and support. Conclusion: The PDS II suture offers numerous advantages, including sufficient mechanical strength, absorbability, less invasive surgical approach, and cost-effectiveness. In the future, additional cases can be provided to further discuss its pros and cons.