- 期刊
病例報告：貓之貓傳染性腹膜炎
Case Report: Feline Infectious Peritonitis in a Cat
摘要
病貓為一隻2月齡，由私人動物收容中心收養之雄性流浪貓，於就診前一星期開始出現厭食、腹部膨脹及消瘦等症狀。血液學檢查呈現顯著的白血球增高（43,100/μL），伴隨嗜中性球增多及淋巴球減少，血清生化學檢查其氨基丙酸轉氨酶（ALT）、天門冬酸轉氨酶（AST）與總膽紅素（Bili. t）顯著上升，白蛋白與球蛋白比值為0.36。抽取病貓腹水分析，細胞學檢查下可見多量非退行性嗜中性球，Rivalt's test判定為陽性，並萃取腹水所含之核酸，利用反轉錄聚合酶鏈鎖反應技術偵測貓冠狀病毒核酸，定序比對確定為貓冠狀病毒。死亡後，剖檢發現胸腹腔臟器皆有多發局部針狀白點病灶，並有纖維素性物質黏附。顯微病變於肺臟呈現多發局部肉芽腫病灶，肝、脾、腸及膀胱則可見肉芽腫性血管炎，淋巴組織則出現顯著的淋巴球嚴重流失及壞死。根據實驗室檢查及病理學的特徵性變化，診斷為貓傳染性腹膜炎。
並列摘要
A 2-month-old male stray cat in private animal shelters was referred to the Vet-erinary Medical Teaching Hospital of National Chiayi University for anorexia, abdominal distension and weight loss since one week ago. Complete blood count showed the apparently leukocytosis (43,100/μL) with neutrophilia and lymphopenia. Serum biochemiacal analysis revealed alanine aminotransferase (ALT), aspartate aminotransferase (AST) and total bilirubin (Bili. t) were elevated apparently, and albumin/globulin ratio was 0.36. Ascites analysis showed the numerous non-regressive neutrophils, and the result of Rivalta's test was positive. Extracting the nucleic acid of ascites followed with reverse transcription polymerase chain reaction (RT-PCR) detected feline coronavirus, and the result was positive. At necropsy, there were multifocal acicular white lesions on the viscera and fibrinous material adhesion. Histopathologically, multifocal granuloma lesions of lung, and granulomatous vasculitis were found on liver, spleen, intestines and urinary bladder. Lymph nodes and other lymphoid tissues appeared significant lymphocyte loss and necrosis. According to the characteristic changes of laboratory tests and histopathological, the final diagnosis was feline infectious peritonitis.