- 期刊
Efficacy of Endometrial Thickness, Pattern, and Vascular Impedance of the Uterine Artery in Predicting the Outcome of Artificial Insemination: Preliminary Report
子宮內膜之厚度，形態，與子宮動脈之血流，用於預測人工授精之懷孕率
摘要
本研究之目的在於決定子宮內膜之厚度，形態，與子宮動脈之血流，用於預測不孕症病患接受卵巢刺激與人工授精（intrauterine insemination，lUI）之懷孕機率。所有病患於接受人工授精當日均測量其了-宮內膜厚度，形態（三層形態與非三層形態），與子宮動脈之脈搏係數（pulsatility index，PI）與阻力係數（resistance index，RI）。進一步評估子宮內膜厚度，形態，與子宮動脈之PI／RI值用於預測lUI成功率之價值。共有37次週期納入本研究中，其中包括6次懷孕週期。懷孕病患中三層形態子，自內膜之比率高達100%，非懷孕病患、中三層形態子宮內膜之比率為多1.6%。所有擁有三層形態子宮內膜病患之懷孕率為27.3%，所有非三層形態子宮內膜病患之懷孕率為0%。懷孕病患之子宮內膜厚度與子宮動脈之PI／RI值為（11.7±2.3mm；2.7±05／0.7±0.3），與非懷孕病患之子宮內膜厚度與子宮動脈之PI／RI值（11.2±2.8mm；2.8±0.7／9±0.4）比較後並無統計學上之美異。總結而言，三層形態之子宮內膜提供一有效之lUI懷孕預測值。子宮動脈之PI／RI個並無法有效用於預測lUI之懷孕率。
並列摘要
The aim of this study was to assess the roles of endometrial thickness, patterns and vascular impedance of uterine artery in predicting the pregnancy outcomes of patients receiving controlled ovarian hyperstimulation (COH) and intrauterine insemination (IUI). All infertile women who accepted COH and IUI were prospectively included. The endometrial thickness and patterns (trilaminar, non-trilaminar), and the vascular impedance [pulsatility index (PI), resistance index (RI)] of the uterine artery were measured on the day of IUI. The predictive values of endometrial thickness and patterns and uterine Doppler flow upon the pregnancy outcomes were made. A total of 37 patients with cycles were included in this study, which resulted in six pregnancy cycles. Trilaminar endometrium appeared in 100% and 51.6% of pregnant and non-pregnant women, respectively. The pregnancy rates in trilaminar and nontrilaminar groups were 27.3% and 0%, respectively. The endometrial thickness and PI/RI values of the uterine artery in the pregnant women (11.7±2.3mm; 2.7±0.5/0.7±0.3) were not statistically different from those of the non-pregnant women (11.2±2.8mm; 2.8±0.7/0.9±0.4). We concluded that a trilaminar endometrium on the day of IUI was predictor of pregnancy. The Doppler surveys of uterine arteries could not be used as a parameter for prediction of pregnancy in COH and IUI patients.