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Passenger Lymphocyte Syndrome after Single Lung Transplantation: Report of a Case and Literature Review

單肺移植後的過渡性淋巴球症候群:一病例報告和文獻回顧

摘要


當血型O型的捐贈者器官移植給血型A 、B或AB型的病患時,可能會發生過渡性淋巴球症候群,理想的情況下,大部份移植手術採用血型ABO型完全相同的器官,有時,因為器官的短缺A、B或AB型的病患會使用O型捐贈者的器官,而造成輕微血型的不配合。在單肺移植手術中,因輕微血型不配合而由捐贈器官的抗體引起的紅血球破壞,較少被報告。我們報告一位A型血型病患,在接受一位O型捐贈者做單肺移植後 8天到11天,造成紅血球溶血,而需要輸血的病例。

並列摘要


Passenger lymphocyte syndrome (PLS) may occur when an organ from a blood group O donor is transplanted into a blood group A, B, or AB recipient. ABO-identical organs are used in the majority of transplants. However, because of the shortage of suitable donors, a minor ABO-mismatch may occur when using blood group O donor organs in A, B, or AB recipients Induction of red blood cell destruction by graft-derived antibodies after minor ABO-mismatched single lung transplantation (SIT) is rare. We describe a blood group A recipient who had hemolysis of red cells, starting from day 8 and lasting up to day 11 after SLT, which necessitated transfusion from a blood type group O donor.

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