The aim of this article is to provide two case reports about autotransplantation, combined with orthodontic treatment , and to summarize the surgical principle ,indications for better survival and success rate. In the past, missing teeth in children are a particular challenge . The only thing orthodontic doctors could do , is to redistribute the space ,according to final prosthesis plan. In recent years, auto-transplantation of developing premolars received increasing attention. The dentists should have the knowledge to recommend and carry out this procedure to the appropriate patient to benefit from nature teeth preserving rather than a mechanical prosthesis.