A 66-year-old male with uremia under peritoneal dialysis complained about consistent hiccup for half a year. Constipation, high creatinine level and hyperglycemia were also noted. On the basis of traditional Chinese medicine theory, he was diagnosed with" block and repulsion" and "internal blockade of water-poison" . The use of Chinese medicine "Da Cheng Qi Tang" plus other herbs for one week to enhance detoxification received an instantly curative effect. How to keep symptom stable and to consistently improve needs further study.