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摘要


肌少症是一種肌肉質量與肌力隨著年齡減少,並伴隨身體功能障礙的老年病症候群。多重因子包括衰老、失用、內分泌與免疫系統的改變都與肌少症有關。肌少症會增加身體活動功能障礙、跌倒與死亡的風險。目前有數個國際共識會議提出有關肌少症的定義與診斷標準。漸進式阻力運動及營養介入是目前被視為可以預防及改善肌少症的有效方法。本文將簡介肌少症的成因、定義、盛行率、篩檢及介入方式。

關鍵字

肌少症 老人 肌肉

並列摘要


Sarcopenia is a geriatric syndrome characterized by age-related loss of muscle mass and strength, and impaired physical function. The causes of sarcopenia are multifactorial, including senescence, disuse, and altered metabolic and immune systems. The consequences of sarcopenia include poor functional status, falls and mortality. Currently there are several definitions and diagnostic criteria for sarcopenia from different international consensus conferences. Clinically there are several screen strategies for sarcopenia. Progressive resistance training and nutritional intervention are beneficial to improve skeletal muscle strength and physical activity in the elderly. This review introduces the pathophysiology, definition, prevalence, screen tools and appropriate intervention of sarcopenia.

並列關鍵字

sarcopenia the elderly muscle

參考文獻


Cederholm, T. E., Bauer, J. M., Boirie, Y.,Schneider, S. M., Sieber, C. C., & Rolland, Y.(2011). Toward a definition of sarcopenia.Clinics in Geriatric Medicine, 27(3), 341-353. doi:10.1016/j.cger.2011.04. 001
Cruz-Jentoft, A. J., Baeyens, J. P., Bauer, J. M., Boirie, Y., Cederholm, T., Landi, F., … Zamboni, M. (2010). Sarcopenia: European consensus on definition and diagnosis. Age and Ageing, 39(4), 412-423. doi:10.1093/ ageing/afq034
Cruz-Jentoft, A. J., Landi, F., Schneider, S. M.,Zúñiga, C., Arai, H., Boirie, Y., …Cederholm, T. (2014). Prevalence of andinterventions for sarcopenia in ageing adults: A systematic review. Report of theInternational Sarcopenia Initiative(EWGSOP and IWGS). Age and Ageing, 43(6), 748-759. doi:10.1093/ageing/afu115
Dawson-Hughes, B., & Bischoff-Ferrari, H.(2016). Considerations concerning thedefinition of sarcopenia. Osteoporosis International. doi:10.1007/s00198-016-3674-8
Fielding, R. A., Vellas, B., Evans, W. J., Bhasin,S., Morley, J. E., Newman, A. B., …Zamboni, M. (2011). Sarcopenia: An undiagnosed condition in older adults. Current consensus definition: Prevalence, etiology, and consequences. International working group on sarcopenia. Journal of theAmerican Medical Directors Association, 12(4), 249-256. doi:10.1016/j.jamda.2011.01.003

被引用紀錄


黃柏銘、廖淇驊、周律廷、許書福、呂怡惠、何旭華(2021)。中西照護活動對於社區預防及延緩失能失智之經驗探討中醫藥研究論叢24(1),55-64。https://doi.org/10.6516/TJTCM.202103_24(1).0005
張籃茵、黃心樹、徐永年、劉紋妙(2020)。下肢運動改善中高齡者的功能性體適能、基本生理指標、運動自我效能、睡眠品質及心理健康護理雜誌67(2),33-44。https://doi.org/10.6224/JN.202004_67(2).06

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