How an urbanite responds to the impact of stressful workload and marital setback is portrayed in Frances Mayes's Under the Tuscan Sun as a therapeutic process for the rehabilitation of personal integrity. As a professor and writer living in San Francisco, Mayes intends to buy a century-old house in Italy. It proves to be a fruitful venture for her to achieve equilibrium between mind and body by living a border life in the middle landscape between civilization and wilderness. With a basic account of the concepts of sense of place, border life, and man-nature relationship, this paper explores the process of Mayes's quest for place and identity.