Silver-Containing Hydrofiber Dressing is an Effective Adjunct in the Treatment of Pemphigus Vulgaris

含銀親水性纖維敷料對於天疱瘡是一種有效的輔助療法

吳介山(Chieh-Shan Wu) ； 許慧玉(Hui-Yu Hsu) ； 胡楚松(Chu-Sung Hu) ； 邱綉惠(Hsiu-Hui Chiu) ； 陳國熏(Gwo-Shing Chen)

《The Kaohsiung Journal of Medical Sciences》 25卷11期 (2009/11) Pp. 622-627

摘要

天疱瘡是一種有可能致命的皮膚水疱病，它的治療對醫療團隊是一個很大的挑戰。目前主要的治療方法是口服類固醇或免疫抑制劑，可是外用藥也扮演重要的角色。我們在此報告一位天疱瘡的病人，病灶面積已侵犯體表面積百分之六十二，起初對口服類固醇及外用磺胺銀軟膏治療效果不彰，但是將換藥方式改用含銀親水性纖維敷料之後，傷口癒合有明顯改善，而且病人的不舒服感也降低。因此，含銀親水性纖維敷料對於影響病灶範圍較大的天疱瘡病人是一種有效的輔助療法。我們對於這種敷料的成功經驗，可以應用到其他傷口範圍大而且滲出液較多的疾病。

關鍵字

天疱瘡 ； 含銀親水性纖維敷料 ； 傷口癒合

並列摘要

Pemphigus vulgaris is a life-threatening autoimmune bullous dermatosis and its management represents a major challenge to medical teams. The primary treatments for pemphigus vulgaris are oral steroids and immunosuppressants, but topical approaches also play a role in disease management. Here, we report a patient with pemphigus vulgaris involving 62% of the total body surface area, with initial poor clinical response to systemic steroids and topical silver sulfadiazine therapy. However, a marked improvement in wound healing and decreased patient discomfort were observed after application of silver-containing hydrofiber dressings (Aquacel-Ag(superscript ®)). Therefore, silver-containing hydrofiber dressings may offer an effective adjunct in the treatment of patients with pemphigus vulgaris with extensive skin involvement. Our encouraging experience with these dressing patches may be extended to manage other large exudation wounds.

並列關鍵字

pemphigus vulgaris ； silver-containing hydrofiber dressing ； wound healing