本研究的目的是在探求及分析正常的華人新生兒胎盤重量及出生特質的關系。此研究包含了從2000年10月至2001年4月的552位近足月出生且無併發症的單胞胎新生兒。研究過程中,我們記錄了母親的年紀、嬰兒性別、妊娠週數、胎盤重量、出生體重、身長、是否早期解出胎便及是否有臍繞頸,並且也計算體重與身長比值、胎兒與胎盤重量比值、及龐德羅指數。結果顯示新生兒的平均出生體重、身長、胎盤重量、平均體重與身長的比值、平均胎兒與胎盤重量的比值、及平均龐德羅指數分別爲3235±17公克、48.8±0.1公分、646.2±0.3公克、66.2±0.3、5.1±0.1及2.8±0.0。男嬰的體重與身長有意義的較女嬰的體重(P<0.05)與身長(P<0.01)大,但胎盤的重量在男嬰及女嬰間則沒有差異。胎盤的重量與出生體重(r=0.413,P<0.01)、身長(r=0.305,P<0.01)、體重與身長的比值(r=0.397,P<0.01)及臍帶長度(r=0.264,P<0.01)均呈現正相關。至於懷孕週數(35-41週)的分組、母親的看似的分組、早期解胎便與否、或是否有臍繞䮲則與胎盤的重量不具有意義的相關。受分析的這群新生兒中、81.9%及69.4%的新生兒發別沒有早期解胎便及臍繞頸的情形。另外、胎兒與胎盤重量的比值和是否早期解胎便、是否有臍繞頸沒有有意義的差別。本研究的結論是胎盤重量對胎兒的體重、身長及臍帶長度有正面的影響,但胎盤的重量與是否早期解胎便、是否有臍繞頸無關。
To determine the relationship of placental weight and birth characteristics of healthy Chinese singleton newborns, 552 consecutive singleton near-term and uncomplicated pregnancies were enrolled in a retrospective study from October 2000 to April 2001. Maternal age, infants' gender, gestational age, placental weight (PW), birth weight (BW), birth length (BL), cord length, ponderal index, and appearance of meconium-stained amniotic fluid or a nuchal cord were recorded and analyzed. Our results show that the mean value of BW was 3235±17 g, birth length was 48.8±0.1 cm, PW was 646.2±0.3 g, BW/BL was 66.2±0.3, BW/PW was 5.1±0.1, and ponderal index was 2.8¡À0.0, respectively. Male neonates had significantly larger BWs (p<0.05) and BLs (p<0.0l) than did female neonates. However, there was no significant difference in PW between male and female neonates. PW was positively correlated with BW (r=0.413, p < 0.01), BL (r=0.305, p<0.0l), BW/BL (r=0.397, p<0.0l), and cord length (r=0.264, p<0.0l). The PW of studied infants showed no significant difference when grouped by gestational age, maternal age, presence of meconium stained amniotic fluid, or presence of a nuchal cord. Of the studied healthy neonate, 81.9% and 69.4% had no meconium-stained amniotic fluid or nuchal cord, respectively. There were no significant differences in PW or BW/PW between neonates with the presence or absence of meconium-stained amniotic fluid or a nuchal cord. These results indicate that PW has a significant role in fetal growth in terms of weight, body length, and cord length. Furthermore, it has no significant role in the presence of meconium-stained fluid or a nuchal cord in healthy neonates.