- 期刊
Influenza B Virus Associated Pneumonia: Report of One Case
B型流行性感冒病毒性肺炎：一病例報告
摘要
流行性感冒病毒引發肺炎時有所聞，但大多數由A型病毒所引起。流行性感冒病毒性肺炎導致急性呼吸窘迫症假群的病例極爲少見，但是死亡率卻很高。除了肺炎之外，流行性感冒病 時可以引起腦部、心臓、腎臓、肌肉等併發症。然而有關流行性感冒病毒引起暫時性肝功能異常的論述並不多。一位七歲原本健康的女孩罹患上呼吸道感染，在7天內迅速惡化成大葉性肺炎和急性呼吸窘迫症候群伴隨肝腫大及肝功能的異常，因而被轉至加護病房使用氣管內管及呼吸器。病毒培養和血清學檢查證實由B型流行性感冒病毒所引起。呼吸道病毒如呼吸道融合病毒是兒童肺炎常見的原因，箉是對於白血球數目及CRP值持續偏低，所有的細菌培養都沒有結果，加上使用抗生素依然無法改善病情的病例應該要將呼吸道病毒列入考慮。有關此病人的病程、診斷和治療將被說細描述。我們提出此一病例目的在提醒大家：B型流行性感冒病毒可以引起暫時性的肝功能異常，磆也是導致小兒肺炎和急性呼吸窘迫症候群的原因之一。
並列摘要
Influenza A virus is a more common cause of pneumonia than influenza B virus. Influenza virus pneumonia complicated with acute respiratory distress syndrome (ARDS) is rare and has a high mortality rate. In addition to pneumonia, influenza occasionally causes neurologic, cardiac, renal, or muscular complications. Hepatic involvement in influenza virus infection has been rarely reported. We reported the case of a 7-year-old girl who was initially treated for upper respiratory tract infection, but she was transferred to the pediatric intensive care unit for intubation and ventilation after her condition deteriorated to lobar pneumonia with ARDS and liver function impairment within 7 days. Influenza B virus infection was confirmed by virus culture and serological study. Respiratory viruses, such as respiratory syncytial virus, adenovirus, influenza virus, and parainfluenza virus, are common causes of pneumonia in children; moreover, they should be considered especially in the presence of persistent leukopenia, low CRP value, lack of growth of bacterial cultures, and poor response to antimicrobial therapy. We should describe its course, diagnosis, and treatments in detail; furthermore, we reported this case to emphasize that influenza B virus may cause transient liver dysfunction and it is an etiology of pneumonia as well as ARDS.