Medicinal Action and Interaction of Androgens and Green Tea Epigallocatechin Gallate

男性賀爾蒙與綠茶成分-EPIGALLOCATECHIN GALLATE之醫療功效及相互作用機制

廖述宗(Shu-Tsung Liao) ； 高永旭(Yung-Hsi Kao)

《The Changhua Journal of Medicine》 6卷2期 (2001/04) Pp. 61-67

摘要

綠茶萃取物應用於人體醫療已有三千多年的歷史，男性賀爾蒙用來當藥物使用也有兩千年之久。最新研究証據顯示，綠茶Cathechin, (-) epigallocathechin-3-gallate (EGCG)，有調節男性賀爾蒙及其他人體賀爾蒙之製造及生物功能的作用。男性賀爾蒙及EGCG也可以用來治療許多因賀爾蒙失調所引起的病症如攝護腺癌、禿頭及青春痘等。EGCG還可以幫助達到節食減肥的目的。其作用機制可能與neuropeptide(s)有關。

關鍵字

男性賀爾蒙 ； 綠茶 ； 攝護腺癌 ； Cathechin ； 肥胖症

並列摘要

Green tea extracts are among the most broadly used ancient (＞3,000 years) medicinal agents in man's history while androgens are probably the oldest (＞2,000 years) drugs used in purified forms. It is now clear that a specific green tea catechin, (-) epigallocatechin-3-gallate (EGCG), can modulate the production and biological actions of androgens and other hormones. Androgens and EGCG can be also useful in treatment of various hormone-related abnormalities such as benign prostate hyperplasia, baldness, and acne, as well as the androgen-dependent and independent prostate cancers. EGCG can also restrict food intake and control obesity and this effect may be dependent of neuropeptide(s) other than leptin.

並列關鍵字

male hormone ； green tea ； Catechin ； prostate cancer ； obesity