- 期刊
Risperidone引起之陰莖持續勃起：個例報告
Risperidone Induced Priapism: A Case Report
摘要
背景及目的：抗精神病藥物的使用雖然有其療效，但副作用的產生卻常常困擾患者本身；其中，有關性功能方面的副作用，往往因為患者不好意思講，或者並不瞭解此副作用與藥物有關而遭到疏忽。陰莖持續勃起(priapism)是性功能副作用中少見的情況，尤其是使用非典型抗精神病藥物-Risperidone。因此本文擬就臨床上發生的案例提出報告，並針對相關文獻作一個回顧，寄望能對造成此一情形的原因有更深入的瞭解。 病例報告：本文報告一位未婚男性患者，在服用Risperidone約兩星期後出現陰莖持續勃起之情形，而在經過住院治療後造成持續勃起功能障礙約兩個月的案例。 結論：陰莖持續勃起雖然少見，但卻是服用治療藥物後可能發生的副作用。臨床醫師在使用抗精神病藥物（尤其是非典型抗精神病藥物）來治療患者之際，也不要忽略了此種可能對病患造成相當影響之副作用。同時，一旦發生此副作用時，也應當謹慎處理，以避免造成更進一步的傷害。
並列摘要
Background and purpose: Priapism is a rare adverse effect resulting from antipsychotics, especially atypical antipsychotics-Risperidone. In a review of the literature in the PsycINFO database collected from 1887 to 2001, there are only three case reports regarding priapism caused by Risperidone. We present a patient experiencing priapism after adminstration of Risperidone and discuss the literature. Case report: A 36-year-old single man experienced prolonged penile erection (which subsided spontaneously) after two weeks treatment with Risperidone. The patient remained impotent for about two months even after prompt management while penile erection lasted for more than twenty-four hours. Conclusion: Priapism is a rare but possible side effect associated with antipsychotic therapy. Increased awareness of the relationship between priapism and antipsychotics (especially atypical antipsychotics) and proper intervention should lead to a decreased further damage and consequence.