- 期刊
Ivermectin、Levamisole 和Imidacloprid & Permethrin對犬東洋眼蟲之療效
Treatment Effects of Ivermectin, Levamisole, and Advantix(superscript ®) for Thelazia Callipaeda in Dogs
摘要
本研究目的在評估使用ivermectin、levamisole 和imidacloprid & permethrin (Advantix(上標 ®))治療犬東洋眼蟲之療效。東洋眼蟲(T. callipaeda)，屬人畜共通寄生蟲，寄生後常見明顯異物感、淚溢、疼痛，搔抓或磨蹭眼部行為，而導致結膜炎、角膜炎、角膜混濁甚至潰瘍等程度不一之症狀。目前控制東洋眼蟲的方法仍以鑷子直接夾除蟲體、並輔以點眼或全身性注射殺蟲藥為主。本研究共7隻病犬，部份犬隻頻繁搔抓眼睛，並出現眼分泌物，下眼瞼結膜囊腔內見細長蟲體。蟲體夾出以電子顯微鏡依形態學鑑定為東洋眼蟲。將7 隻病犬分組後分別以ivermectin、levamisole和imidacloprid & permethrin 進行治療。結果一個月後，所有病犬皆未發現眼蟲，且未見臨床症狀。但使用2% levamisole溶液點眼，可能造成犬隻眼部刺激呈不舒適感。持續追蹤使用藥物三個月後，所有病犬皆仍無眼蟲復發及臨床症狀出現。
並列摘要
The aim of this research was to evaluate the effects of ivermectin, levamisole, and imidacloprid & permethrin (Advantix(superscript ®)) for Thelazie callipaeda infection in dogs. Clinical symptoms include epiphora, and ache of the eye. Conjunctivitis, keratitis, and cornea ulceration may also be observed. Treatment modalities include directly removing the worm with forceps, application of eye drops and injection. Seven Thelazi-infected dogs with frequent scratching and rubbing of the eyes as well as ocular discharge were used in this study. Numerous white translucent worms were observed in the subconjunctiva sac. The species was confirmed to be The/az/a cal/ipaeda by EM. The infected dogs were divided into 3 groups for treatment with ivermectin, levamisole and imidacloprid & permethrin. One month later, all dogs were free of the parasite. The 2% levamisole solution may cause discomfort. Follow up for 3 months showed no evidence of T callipaeda infection in any of the treated dogs.