- 期刊
Prolapsing Mucosal Polyps without Prolapse of Rectal Mucosal-Report of 7 Cases
黏膜性瘜肉脫垂—7病例報告
摘要
目的 黏膜性瘜肉脫垂(prolapsing mucosal polyps)最早於1985年被提出，爲新定義之良性結腸瘜肉，合併黏膜脫垂症狀爲其特徵，本研究收集7例黏膜性瘜肉脫垂並？？？。 方法 本研究回顧並收集財團法人長庚紀念醫院之病理學資料庫於2002至2005年間，經診斷患有結瘜肉，且病理診斷結果爲黏膜性瘜肉脫垂之病患共7位。 結果 7位病患中有3位男性、4位女性，年齡分布自30至86歲。所有患者之瘜肉皆分佈於乙狀結腸或直腸位置，且皆無憩室症、直腸單一潰瘍症候群(solitary rectal ulcer syndrome)、或黏膜脫垂等症狀。組織學觀察方面呈現下列一致的結果：隱窩(crypt)異常、固有層(lamina propria)之纖維肌肉閉塞症(fibromuscular obliteration)、瘜肉內黏膜肌層外展至固有層內、發炎細胞滲透至固有層內以及黏膜微血管異常等。 結論 黏膜性瘜肉脫垂爲一罕見症狀，且組織學觀察結果與結腸瘜肉相異，並與直腸黏膜脫垂無關。
並列摘要
Background. Prolapsing mucosal polyps were first described in 1985 as a new entity of benign colorectal polyp and were characterized by the association with mucosal prolapse. We examined and analyzed a series of seven cases with such lesions in hope of clarifying the clinicopathological features of this rare entity. Methods. From the Database of Pathology in Chang Gung Memorial Hospital from 2002 to 2005, we retrospectively identified and studied seven patients who had a colorectal polyp with a pathologic diagnosis of prolapsing mucosal polyp. Results. There were three male and four female patients. Their ages ranged from 30 to 86 years. All the polyps were located in the sigmoid colon or rectum. None of the patients had diverticular disease, solitary rectal ulcer syndrome, or symptoms of mucosal prolapse. The most consistent histological findings were: crypt abnormalities, fibromuscular obliteration of the lamina propria, splayed muscularis mucosae into lamina propria in the polyp, inflammatory cells infiltration in lamina propria and mucosal capillary abnormalities. Conclusions. Prolapsing mucosal polyp is a rare but histologically distinct type of colorectal polyp, which may be not associated with clinical evidence of rectal mucosal prolapse.