- 期刊
Colorectal Cancer in Patients under the Age of 40: Tri-Service General Hospital Experience
四十歲以下大腸直腸癌病患：三軍總醫院經驗
摘要
背景 大腸癌是國人第一好發及第三死亡率的癌症，近年來，大腸癌的病患有年輕化的趨勢，本篇文章的目的是以回溯性研究的方式對單一醫學中心中40歲以下大腸直腸癌病患進行分析。方法 回溯性病例回顧於2007年1月至2011年12月，搜索本院癌症登記資料庫40歲以下，且診斷為大腸癌的病患，分析病患平均年齡、性別、腫瘤性質、分期、發生位置以及治療方式預後等進行討論。結果 共52位病患，男性34人、女性18人，症狀最常見為肛門出血，除4位類癌病患，其他48人均為腺癌，以3、4期最多共36位，分化以中度28位最多，部位以直腸最多佔23位，其中3期病患平均存活4.1 ± 0.6年，4期病患平均存活1.8 ± 0.5年。結論 所有有大腸癌相關症狀的40歲以下之病患，建議接受大腸癌相關檢查，以早期發現、早期治療。
並列摘要
Background. In Taiwan, colorectal cancer is the first common cancer and is the third most common cause of cancer related death. In recent years, patients with colorectal cancer became younger. The purpose of this study was to analyse the patients under the age of 40 years suffering colorectal cancer. Material and Methods. We conducted a retrospective study in Tri-Service General Hospital. From January 2007 to December 2011, patients under the age of 40 years with colorectal cancer were included. Patient demographics, tumor type, tumor stage, tumor differentiation, tumor location, treatment and mean survival time were analysed. Results. Totally 52 patients, including 34 males and 18 females had colorectal cancer under the age of 40 years. The most common symptom was anal bleeding. Except 4 patients with carcinoid, all of the other patients had adenocarcinoma. Thirty-six patients had stage III/IV at diagnosis. Twenty-eight patients with adenocarcinoma had moderate differentiation. Twenty-three patients suffered from rectal cancer. Mean survival time of adenocarcinoma of colo-rectum was 4.1 ± 0.6 years in stage III patients, and 1.8 ± 0.5 years in stage IV patients. Conclusion. All patients with suspicious symptoms of colorectal cancer merit undergoing large bowel evaluation.