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Case report: recovery trajectory of a patient with autoimmune anti-GABAB receptor encephalitis

GABA_B受體腦炎患者的康復軌跡個案報告

Abstracts


Autoimmune anti-GABA_B receptor encephalitis is a rare form of limbic encephalitis that typically has an initial neuropsychiatric presentation followed by sequalae. Here, we present a case of anti-GABA_B receptor encephalitis confirmed by cerebrospinal fluid testing and a corresponding left temporal lobe lesion detected by brain magnetic resonance imaging (MRI). Longitudinal evidence from clinical observation, brain MRIs, and the ascending trajectory of his cognitive performance confirmed that the repeated high-dose corticosteroid pulse therapy effectively halted the patient's disease progression with favorable responsiveness.

Parallel abstracts


自體免疫性抗GABA_B受體腦炎是一種罕見的疾病,在最初的神經精神症狀發生後,也常伴隨後遺症。我們提出一例經腦脊液檢測證實的抗GABA_B受體腦炎病例,並由磁振造影成像(MRI)檢測到相應的左顳葉病變。透過長時間追蹤與臨床觀察、多次腦部磁振造影成像和認知功能,持續記錄其康復軌跡,提出縱貫性證據,並且在此個案中,使用重複大劑量皮質類固醇衝擊療法,有效地阻止了患者的疾病惡化並具有良好的反應性。

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