- 期刊
Amisulpride Implicated in the Onset of Tardive Dyskinesia in a Man Who Previously Took Sulpiride
Amisulpride導至一位之前服用sulpride的男性產生遲發性運動不能
摘要
Amisulpride及sulpiride是比較不會引起急性錐體外症狀的藥物，然而我們報告一個52歲的男性妄想型精神分裂病人，他因為反覆的急性精神症狀發作而接受amisulpride，雖然活性症狀的改善，但遲發性運動不能在接受該藥後不久就發生。不自主運動在改成risperdone後有些微改善，因此，雖然amisulpride是比較不會產生椎體外症狀，它依然有可能產生遲發性運動不能的危險性存在。
並列摘要
Both amisulpride and sulpiride are less associated with acute extrapyramidal symptoms. However, we report the case of a 52 year-old man with schizophrenia who received amisulpride due to the recurrence of acute psychotic symptoms. Despite improvement over positive symptoms, tardive dyskinesia developed soon after using amisulpride. The involuntary movements were slightly improved after amisulpride was cross-tapered to risperidone. Although lower risk of extrapyramidal symptoms is associated with amisulpride, there is still some risk of developing tardive dyskinesia.