Mesenteric phlebosclerosis is a rare disease. The pathogenesis of this disorder is inconclusive. It has been proposed that there is a slow, but long-standing hypoxic injury to the venous muscular layer, leading to gradual mummification, sclerosis, and calcification of the venous muscles. This is followed by damage to the reactive hyperplastic myointima in the veins, leading to gradual venous occlusion. Disturbance of venous return results in secondary ischaemic colitis. The right-sided colon is the most often affected bowel segment in previous report. The exact aetiology remains unknown. Thisreport presents the relevant radiological features in a female with mesenteric phlebosclerosis. The clinical and pathological aspects of this entity are also discussed.