The patient of this case study suffered from acute onset of chronic hepatitis. We apply YinChenHaoTang and YiGuanJian with oral Baraclude, a nucleic acid analogue, and the patient's GOT/GPT dropped from 1097/2566 to 120/481 within half month, and both indexes dropped within normal range within one month. On top of that, patient's HBV DNA dropped to 0 from 2.3×10^6. JiaWeiXiaoYaoSan, ZhiBoDiHuangWan and digestive medication are applied in maintenance stage to regulate the mechanism of liver, spleen and kidney to reach the optimal recovery physically and mentally. The side effect of Baraclude is reduced dramatically with only minor complaint of loose stools. Follow-up after 6 months shows satisfying result, so we can further study integrated Chinese and Western medicine on acute hepatitis.