This 19 y/o female had past history of atopic dermatitis treated with antihistamine agent, and she received traditional Chinese medicine due to relapsed symptoms. After taking Chinese for about 2months, she started to have fever, epigastric pain and abnormal liver function. She was admitted under the impression of acute hepatitis which might be herbs related. Allergic reaction was also noted, so special constitution related acute hepatitis was suspected. Herbs are commonly used in Chinese society, so doctor must keep in mind that herbs might induce allergic reaction and hepatic toxicity.