This is a 45-year-old female who suffered from hypoxic coma as a side effect of heart attack. During hospitalization, her symptoms were lost of consciousness, seizure, respiratory failure, unstable hemakinetics and high, unsettled fever with no specific reason. Antibiotic was used with no significant improvement. After consultation, TCM doctors prescribed An Gong Niu Huang Wa for her patterns of phlegm and heat disturbing the heart, closed orifices and coma. The patient's fever started to subside. Acupuncture treatment was introduced later, and the patient was off respirator and started to wake up after that. GCS at the beginning of hospitalization was E1VeM4, and it was E4V2M6 when she was discharged. This is a fairly successful case of treating hypoxic coma with fever by integrating Chinese and Western medicine.