- 期刊
上泌尿道移行上皮癌：40例之經驗與文獻回顧
Upper Urinary Tract Transitional Cell Carcinoma-The Experiences of 40 Cases and Literature Review
摘要
上泌尿道移行上皮癌指移行上皮癌而原發生於腎盂、腎盞或不同部位之輸尿管，在南台灣並不少見。泌尿道上皮癌因俱有潛伏顯微多發之特性，因而上泌尿道移行上皮癌雖然經過外科手術治療，仍有一定比例再復發上皮癌症於下位的膀胱、甚至復發於對側的泌尿器官。本研究回顧過去十年內，經診斷為上泌尿道移行上皮癌而接受外科手術切除治療（或合併術後統計分析各項基本資料。手術治療由一位固定之醫師執行，針對上泌尿道移行上皮癌術後好發於輸尿管殘端或輸尿管開口附近之特性、於每例手術步驟中均確實執行遠端輸尿管端全切除術。病理分期由兩位固定的病理科醫師報告。統計分析疾病的癌細胞分化程度、期別、併發症、復發率、五年存活率，並與其它文獻中之數据結果比較。本研究結果顯示與其它文獻相同之處有（1）女性好發率約為男性的兩倍，其它文獻為：男/女＝3.5/1。（2）復發率較低，可能與T2期（凡有肌肉層侵犯）即接受輔助化學治療得助益有關。
並列摘要
Upper urinary tract transitional cell carcinomas occurs primarily at renal calyx, pelvis and any portion of ureter. It is not a rarely encountered malignant disease in southern Taiwan. Owing to the character of potentially microscopic multi-centric metastasis, the malignancy sometimes recurs at lower urinary bladder and even, to the contralateral collecting system post-operatively. We prospectively reviewed 40 cases diagnosed to be upper urinary tract transitional cell carcinomas. The operative procedures were performed by a fixed urologist, and specimens studied by two senior pathologists. Open method of nephroure-terectomy (ONU) with bladder cuff excision by way of cystotomy and total distal ureterectomy is to prevent high recurrence over the ureteral stump. Adjuvant chemotherapy for cases with muscular layers had been invaded. We collected all basic data and put it to SAS software for statistics. Variances were compared with published literatures.