Small and asymptomatic hypo- pharyngeal diverticulum is likely to be misdiagnosed as a thyroid nodule due to the proximity of the upper esophagus to the thyroid gland. The principles to distinguish between esophageal diverticula and thyroid nodules should be noted clearly to avoid the unnecessary invasive procedures. In the current case, a 32-year-old man presented with a 'suspected malignant thyroid nodule' in the left thyroid gland, and underwent a neck exploration. However, no visible 'suspected thyroid tumor but a sac protruding from the left anterolateral wall of the cervical esophagus, was observed during the surgery. The esophageal mass was resected and the pathology revealed diverticula of esophagus. The patient recovered well after 3 months of surgery. Real-time ultrasonography and pharyngoesophagography are important techniques to distinguish a hypopharyngeal diverticulum from a thyroid nodule. That will help the clinicians to avoid the unnecessary interventions.