- 期刊
Interstitial Cystitis-Cystoscopy, Hydrodistention, Potassium Test, Urodynamics, Pathology-What is the Value of Each?
並列摘要
Interstitial cystitis (IC) is characterized by bladder pain associated with urgency, frequency, nocturia, dysuria and sterile urine. The diagnosis of this disease remains unclear and should be based on exclusion of other diseases. Cystoscopy can be performed to exclude bladder cancer or chronic granulomatous cystitis. Hydrodistention under general anesthesia is the classical diagnostic test to demonstrate glomerulation and mucosal fissure in IC, and can be used to classify the severity of disease as well as the chance of recovery after medical treatment. A potassium chloride test provides a diagnosis of urothelial leak and measurement of therapeutic effect of surface protective treatment. An urodynamic study can differentiate detrusor overactivity from sensory urgency in IC. Low bladder compliance also predicts a poor therapeutic outcome of IC. Pathological examination can diagnose bladder cancer and granulomatous disease of the bladder. Although none of these, even together, is able to diagnose IC adequately, they can provide valuable information on this mysterious disease.