Mangosteen ("Garcinia mangostana" L.) is one of the economically important fruits of Thailand. However, it has been evident that climate change affects the yield and quality of mangosteen fruits. As a result, this may have an impact on economic of mangosteen growers. Therefore, the objectives of this study are: 1) to investigate the effects of climatic variability on mangosteen flowering date in 2 production areas (Nakhon Si Thammarat and Chanthaburi provinces) and 2) to analyze the correlation between the climatic factors and the flowering dates of mangosteen. The results showed that the climatic variability occurred during 1982-2012 both in Nakhon Si Thammarat and Chanthaburi provinces. The average flowering date of mangosteen during the off-season period significantly delayed by 5.10 days/year (p≤0.01). A drying periods before flowering and maximum temperatures affected mangosteen flowering. A model using these climatic factors was developed to predict the flowering date of mangosteen. The model could predict the flowering date with 52.30% accuracy and the estimated standard error was 9.53.