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- OpenAccess
The Effect of Aqueous Methanolic Stem Bark Extracts of Acacia Polyacantha on Sexual Behaviour, Serum Testosterone Levels in Male Wistar Rats
並列摘要
The aim of the research is to determine the possible application of Acacia polycantha in the treatment of sexual behavior and serum testosterone. We determined the LD_50 from the dried bark of the plant to be 3808.88 kg/body weight, then treated the wistar rats with 150, 300 and 600mg/kg body weight that was shown to have effects on mounting behavior which increased from 6.20±2.49 in control to up to 8.40±3.25 with concentration of 150mg/kg and falls to 3.80±1.35 and 0.20+0.20 with 300 and 600mg/kg body weight respectively. On the other hand the testosterone levels increased from 3.62±2.19 in control to 6.88±1.78 with 150mb/kg and 7.18±2.38 and 7.78±2.38 with 300 and 600mg/kg respectively while falling insignificantly below the control to 3.60±1.34 with Viagra 150mg/kg. We concluded therefore based on the experiment conducted that Acacacia polycantha plant could be used to enhance sexual behavior after further screening of its active ingredients.