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Bioactive Studies of Mangifera indica Aganist Bacteria Isolated from Urine Samples

並列摘要


Urinary tract infections are the second most common type of infection in the world. It is usually caused by bacteria such as Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, Klebisella pneumoniae, Streptococcus pyogens etc. Bacteriuria, Pyrexia, Uretheritis, Pyuria, Haematuria are the urinary tract infection, commonly caused by bacteria. Seed kernel of Mangifera indica which has antibacterial, antidiarrhoeal, antioxidant and antiviral activity against the uropathogens isolated from clinical samples. Urine samples were collected from government hospital at Srirangam. The samples were subjected to macroscopic, microscopic, and culturing by selective and differential media and biochemical test to identify the pathogens. Seed kernels of M. indica were extracted by using water and ethanol. Antibacterial activity of M. indica aqueous and ethanol was studied by disc diffusion method, which shows best activity against the clinical isolates at 800μg concentration (19mm). St. aureus is strongly inhibited by the extract. MIC was performed by using agar dilution method. It was found to be between 300mg/ml to 750mg/ml. Phytochemical studies revealed that the presence of Tannin and Steroid. If we develop a good drug from this plant it may be better for human health.

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