Fish, especially when reared in high densities, require a high-quality, nutritionally complete, balanced diet to grow rapidly and remain healthy. Fish gut is a tubular structure beginning from the mouth and ending at the annus. Many fish chew their food and have the ability to secrete mucus substances from the mucus gland. In fish, the enzymes are liberated into the lumen of the gut and the products of their action absorbed (extra cellular digestion). Chromium oxide (Cr_2O_3) mixed with prepared diets, measured in the faeces, provides a general comparison of the digestibility of all feed. A proper understanding of the fish digestive system, description of fish gut, physiology of fish gut, peristalsis and its control, gastric evacuation time, digestion and absorption, Specific Dynamic Action (SDA), characteristics of enzymes and other digestive secretions , digestion in the mouth and oesophagus, digestion in the stomach, digestion in the mid gut and pyloric caeca, the role of bile, gall-bladder and liver in digestion, measurement of digestibility and related factors, feed conversion and efficiency calculations, nutrient requirement, proteins, fats and lipids, carbohydrates, vitamins and minerals are vital for effective culture fisheries.