This study evaluated the effect of Telfaria occidentalis diet on haematological indices in rats. 14 male rats were used, they were divided into two groups; control and test. The control group was fed with normal rat feds while the test group was fed with feeds containing 25% by weight of Telfaria occidentalis for 30 days. The Packed Cell Volume (PCV) and total White Blood Cell count (WBC) were determined. The result shows a significant increase in WBC.