We report the case of a 75-year-old woman who presented with gradually progressive speech disorders and memory impairment. Brain magnetic resonance imaging revealed no significant finding. Technetium-99m ethyl cysteinate dimer brain perfusion single photon emission computed tomography (SPECT) with semiquantitative analysis revealed hypoperfusion in the left hemisphere, predominant on the posterior temporal lobe extending to the posterior parietal lobe. After considering the clinical presentation and SPECT findings, we established a diagnosis of logopenic variant of primary progressive aphasia.
我們報告一位75歲女性案例,其表現為緩慢進行之言語與記憶障礙。腦部磁振造影並無顯著發現。鎝-99m雙半胱乙酯腦血流灌注單光子射出電腦斷層掃描(Tc-99m ECD brain perfusion SPECT)搭配半定量分析顯示左側大腦半球血流灌注下降,主要是在顳葉後部並延伸至頂葉後部。考慮病人的臨床表現以及SPECT發現後,我們建立了缺詞型原發漸進性失語症的診斷。