The pivotal image findings of progressive multifocal leukoencephalopathy: A case report

Shou-De Ma ； Chih-Wei Wei ； Tai-Lin Huang ； Chao-Hsin Wu ； Shiang-Yu Chang

《童綜合醫學雜誌》 18卷2期 (2024/12) Pp. 114-116

https://doi.org/10.4103/etmj.etmj-d-24-00020

摘要

Progressive multifocal leukoencephalopathy (PML) is a rare disease associated with the reactivation of the JC virus, particularly in immunocompromised patients. A 60-year-old woman, who was on immunosuppressive therapy, presented with a sudden seizure and was diagnosed with PML based on magnetic resonance imaging (MRI) findings. Typically, PML appears on computed tomography scans as asymmetric focal zones of low attenuation in the periventricular and subcortical white matter, while MRI findings usually show multifocal demyelination in these areas. The imaging results in this case are consistent with the typical presentation of PML.

關鍵字

Chronic kidney disease ； cyclosporine A ； immunocompromised ； JC virus ； progressive multifocal leukoencephalopathy ； seizure