- 期刊
糖尿病家族史是提高空腹血糖異常型前期糖尿病篩檢效率的重要因子
Family Diabetic History as an Important Factor of Raising the Screening Efficiency of Prediabetes with Impaired Fasting Glucose
摘要
目的：評估糖尿病病患子女血親與社區民眾之糖尿病及前期糖尿病之篩檢成效。方法：醫院實驗組是透過兩家醫院病友會，篩選糖尿病患之子女血親大於30歲(含)以上且無糖尿病史者。社區對照組是以戶籍設於高雄縣大社鄉且年齡大於30歲(含)以上者為母體，採用多階段分層抽樣調查法取得隨機樣本。所有個案於受檢前需空腹八小時，量測體位、血壓、空腹血糖以及膽固醇等生化值，並以標準化結構式問卷收集其人口學及生活習慣相關資料。結果： 醫院實驗組共篩檢174名個案， 結果發現27.0%有前期糖尿病(100-125 mg/dl)，6.3%達到糖尿病診斷的標準(≧126 mg/dl)。與社區對照組(1,379名)比較，發現在調整性別及年齡後，篩檢出前期糖尿病的機率，是社區的2.07倍；而高血壓、年齡及身體質量指數都與前期糖尿病的檢出有關。結論：家族史可提高篩檢前期糖尿病效率，若合併考慮血壓、身體質量指數及年齡等因子時，則可以更加提高篩檢效率，有效降低篩檢成本。
並列摘要
Objectives: To evaluate the effectiveness of screening children and blood relatives of diabetic patients and community residents for diabetes and prediabetes. Method: The children and blood relatives of diabetic patients, aged 30 years or older, from the patient advocacy groups at two hospitals were screened and recruited into a hospital experimental group. A community control group was formed by recruiting residents aged 30 years or older and living in Dashe Township, Kaohsiung. A multistage stratified sampling survey approach was adopted to obtain random samples. All subjects were required to go on an empty stomach for 8 hours before their biochemical values, notably body weight, blood pressure, fasting blood pressure, and cholesterol, were measured. Moreover, a standard structured questionnaire was utilized to gather demography, living habits, and other relevant information. Result: Of the 174 subjects screened in the hospital experimental group, 27.0% had prediabetes (100-125 mg/dl), and 6.3% reached the diabetes diagnosis standard (≧ 126 mg/dl). Comparison with subjects in the control group (1,379 persons) found that, after adjusting gender and age, the probability of detecting prediabetes through screening in the hospital experimental group was 2.07 times greater. High blood pressure, age and BMI appeared to be related to the detection of prediabetes. Conclusion: Examining family history can enhance the efficiency of screening for prediabetes. If blood pressure, BMI and age are combined for consideration, the efficiency of screening will be raised to effectively reduce the screening cost.