It is often difficult for patients with gout to choose their diets. But the risk of gout resulting from purine diet (hight or low purine diet) is not clear. The purpose of this paper is to evaluate the relationship between purine diet and gout attack.We searched the database of the Cochrane Library, PubMed, Trip database and CEPS. We included a paper to fit in with the PECO as a cohort study from Trip database. The results showed that ingestion of purine-rich diet such as meat or seafood increased the risk of gout mostly. Relatively, ingestion of purine-free or low purine diet such as vegetables ,vegetable protein or dairy did not increased the occurrence of gout attack.