目的:本研究旨在探討低能量血管雷射光療法對於人體血球及生化數值的影響。方法:本研究收錄39位在2017年及2018年於衛福部桃園醫院接受血管雷射的患者,並排除先前已接受過相同治療者。分別在個案治療前、治療後一週內、治療三個月後,抽血檢驗血球(白血球、血紅素、血小板)及數項生化數值(總膽固醇、三酸甘油脂、高/低密度膽固醇、空腹血糖、醣化血色素、靜脈氣體分析、紅血球沉降率、免疫球蛋白E),再比較各項數值於治療前後是否有統計學上差異,另對於病患不適反應予以紀錄。結果:三個月後平均血紅素上升0.328±0.970g/dL(p=0.041)、血小板降低25.256±70.110x10^3/uL(p=0.030)、紅血球沉降率下降8.62±20.91mm/hr(p=0.014)、高密度脂蛋白上升3.41±6.27mg/dL(p=0.002)、以及空腹血糖下降5.05±14.22mg/dL(p=0.033)。其他皆未達統計學上差異。結論:本觀察性研究指出血管雷射可於人體產生一些血液及生化改變,且無任何併發症。基於研究結果,將來或許可應用作為疾病的輔助治療。
Objectives. The purpose of this study was to investigate the effects of intravenous laser irradiation of blood (ILIB) therapy on human blood cells and biochemical values. Methods. This trial included 39 patients who underwent ILIB therapy at the Taoyuan General Hospital of the Ministry of Health and Welfare in 2017 and 2018. We measured blood cells (WBC, Hb, platelets) and several biochemical values (total cholesterol, triglyceride, HDL, LDL, fasting blood glucose, HbA1c, venous gas analysis, ESR, immunoglobulin E) before and after treatment to determine which ones might be significantly different. Results. Three months after the ILIB therapy had been completed, the mean value of hemoglobin increased by 0.328±0.970g/dL(p=0.041), the mean value of platelet decreased by 25.256±70.110x10^3/uL(p=0.030), the mean value of ESR decreased by 8.62±20.91mm/hr (p=0.014) , the mean value of HDL increased by 3.41±6.27mg/dL p=0.002), and the mean value of fasting blood glucose decreased by 5.05±14.22mg/dL (p=0.033). The other differences not mentioned were not significant. Conclusion. This observational study suggests that ILIB therapy can produce some blood and biochemical changes in the human body without complications, and that may be used as an adjuvant treatment for some diseases in the future.