PCOS is a complicated gynecological disease and it's also one of the most common ailments that seek medical attention. Symptoms of PCOS include oligomenorrhea or amenorrhea, infertility. Among all the patients with PCOS, about 40% of women with PCOS has insulin resistance. Insulin resistance contributes to androgen excess and chronic inflammation in PCOS and might be the cause of PCOS. The complication of PCOS involves the reproductive system, the central nervous system, and the endocrine system.