Summary: The primary means of scientific research on the therapeutic mechanism of traditional acupuncture has been heavily rely on the utilization of modern medical tools.Therefore, I employed SPECT (Single Photon Emission Computed Tomography) medical imaging technology to observe subtle changes in cerebral blood flow perfusion after stimulation of acupuncture points in the human body.Shou San Li (LI10) acupuncture point is chosen for this experiment. Result: Before and after the simple manual stimulation of Shou San Li (LI10) acupuncture point, the difference in cerebral blood flow perfusion indicates a significant increase in blood volume to the hippocampus, amygdala, and cerebellum regions. If using the combination of acupuncture and moxibustion on Shou San Li (LI10) shows the increased blood flowin certain regions of the hippocampus and cerebellum.