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摘要


鱗狀上皮細胞癌,常發生在年老的人,是皮膚癌中第二常見的腫瘤。因慢性皮膚潰瘍併發骨髓炎並進而於潰瘍內形成鱗狀上皮細胞癌在臨床上並不多見。雖然鱗狀上皮細胞癌多數發生在下肢,但是較少發生在足踝。通常需以病理組織切片來確定診斷。鱗狀上皮細胞癌的細胞分化程度,腫瘤的大小及侵犯的深度與此疾病的癒後有關。腳部之鱗狀上皮細胞癌有可能是原發性,次發性或轉移性的腫瘤,而且有復發的可能性,故廣泛性的切除或截肢是較佳的治療選擇。本患者在接受廣泛性的切除和前大腿外側皮瓣重建之後恢復良好。

並列摘要


Squamous cell carcinoma (SCC), the second most common skin cancer, typically occurs in the elderly. SCC arising from a chronic ulcer with complicating osteomyelitis of underlying bone is a unique clinical manifestation. Although most SCCs occur in the lower extremities, occurrence in the foot and ankle is uncommon. Histological proof is necessary for definite diagnosis. The degree of differentiation of SCC, as well as the size and depth of the tumor invasion, are extremely important prognostic factors. SCC in the foot can be primary, secondary or metastatic in nature and has the potential for recurrence. Wide local excision or amputation is the preferred treatment option. Our patient recovered well after undergoing wide local excision and free anterolateral thigh flap reconstruction.

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